Case Series of Hepatoblastoma

Background: In the past 20 years, a dramatic improvement in the prognosis of patients with hepatoblastoma (HB)has been achieved by combining surgery and chemotherapy in several national and international trials.Materials and Methods: Four children ( 3 girl and 1 boy) aged 34 days, 4 months, 13 months, and 1 year with meanage of 6.53 (±5.15) months were presented to our center from 2002 to 2009 with abdominal mass and abdominaldistention. Their abdominal ultrasonography revealed liver mass, and pathological diagnosis was hepatoblasma.They were treated with a combination of surgery and chemotherapy.Results: Patients with non-metastatic HB were treated at Shahid Sadoughi Hospital of Yazd. A complete resection ofprimary tumor was achieved in all of them. The median follow- up of the patients was 38.25 (± 29.02) month and allof them (100%) remained alive with complete remission.Conclusion: Complete resection with chemotherapy can improve prognosis of hepatoblastoma patients.